Write the meaning: (Act 4) And ‘tis not wisdom thus to second grief against yourself. (scene 1, lines 2-3)

In this line Antonio is warning or advising Leonato that he needs to stop adding to his own grief or problems. Antonio is trying to comfort Leonato who is still grief-sticken over what happened in the church with Hero (his daughter).

Note these lines are from Act V, Scene I.