The play of macbeth
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Besides becoming a paranoid sociopathic murderer, not too much! Okay, let's trace back:
-Kills Duncan (the king)
-Kills Banquo/tries to kill Fleance
-Kills Macduff's family and just about everyone that lives in his castle
-commits treason against his king. Yes, by killing him!
-Really makes God angry by upsetting the universal order of things.