Whenever Dr. Jekyll wants to change into his “darker” side, he seeks isolation. He wants to maintain his respectable role in the community while he engages in activities not acceptable to society. What happens to people when they are not restrained by social conventions?
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This really depends on the person. The idea behind the story is that people, free from social conventions, will indulge in their primal desires or their Freudian "Id." As a respectable member of society and an honorable Victorian gentleman, Jekyll cannot fulfill his evil desires. Without counterbalancing his evil identity, Jekyll allows Hyde to grow increasingly strong, and eventually take over entirely, perhaps entirely destroying all the pure goodness Jekyll ever had.