Answer
-$\frac{1}{10}$x$^8$y$^9$z$^4$
Work Step by Step
Divide the monomials by cancelling out common factors of the numbers and subtracting the exponents of variables.
$\frac{-5x^{10}y^{12}z^6}{50x^2y^3z^2}$=-$\frac{5}{50}$x$^{(10-2)}$y$^{(12-3)}$z$^{(6-2)}$=-$\frac{1}{10}$x$^8$y$^9$z$^4$
Check the answer
50x$^2$y$^3$z$^2$(-$\frac{1}{10}$x$^8$y$^9$z$^4$)=-$\frac{50}{10}$x$^{(2+8)}$y$^{(3+9)}$z$^{(2+4)}$=-5x$^{10}$y$^{12}$z$^6$