A region-1 (U.S. and Canada) DVD version of The Big Sleep was released in 2000. It is a double-sided, single-layer disc; with the 1946 theatrical version on side-A (114 m), and the 1945 version (116 m) on side-B. The 1946 opening credits appear on both versions, including Peggy Knudsen, who never appears in the original version. Nowhere is the original actress, Pat Clark, ever credited. The DVD also contains a 16-minute, edited version of the 1997 documentary comparing the two versions that is narrated by Robert Gitt, who worked on the restoration of the 1945 version. Film critic Walter Chaw writes of the DVD releases of The Big Sleep and To Have and Have Not (1944), "The fullscreen transfer of The Big Sleep is generally good but, again, not crystalline, though the grain that afflicts the earlier picture is blissfully absent. Shadow detail is strong—important given that The Big Sleep is oneiric—and while the brightness seems uneven, it's not enough to be terribly distracting. The DD 1.0 audio is just fine."
A Blu-ray DVD was released by Warner Bros. in 2015. It "includes the 1945 cut of the film that was screened for overseas servicemen, running two minutes longer and containing scenes not used in the official release."