Answer
1. Zone of Resting Chondrocytes: hyaline cartiledge on the epiphyseal (proximal) side of the plate
2. Zone of Proliferation: chondrocytes undergo rapid mitosis which elongates the bone
3. Zone of Hypertrophy: chondrocytes enlarge and begin to secrete alkaline phosphatase (calcification of matrix)
4. Zone of Calcification: chondrocytes are walled off in a calcified matrix, chondrocytes under apoptosis which means death
5. Zone of Ossification: osteoclasts (chondroclasts) break down the calcified matrix, osteoblasts begin forming the spongy bone
Work Step by Step
Bone Growth and Remodeling Pg 211-212
