Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 21 - Section 21.1 - Study Guide - Assess Your Learning Outcomes - Page 844: 3

Answer

**Production of Lymph:** Lymph is derived from the interstitial fluid that surrounds cells in tissues. Interstitial fluid is the fluid that bathes the cells and provides them with nutrients and oxygen while removing waste products. As blood circulates through the capillaries, some of the plasma (the liquid component of blood) leaks out of the capillaries and into the surrounding tissues, forming interstitial fluid. This interstitial fluid is then collected by tiny, specialized vessels called lymphatic capillaries. These capillaries are part of the lymphatic system and are responsible for collecting the interstitial fluid and transforming it into lymph. The collected fluid, now referred to as lymph, is transported through larger lymphatic vessels and eventually reaches lymph nodes, where it undergoes filtration and processing before reentering the bloodstream. **Characteristics of Lymphatic Capillaries:** Lymphatic capillaries have unique characteristics that allow them to collect interstitial fluid, as well as cells and other particles, to form lymph. Here are some of the key characteristics: 1. **Structure:** Lymphatic capillaries have thin walls made of a single layer of endothelial cells, which are loosely connected. This structure creates small gaps or flaps between the cells that allow for easy entry of interstitial fluid. 2. **Valves:** Lymphatic capillaries have one-way valves that prevent the backflow of lymph once it enters the capillary. These valves ensure that once the fluid is inside, it moves in one direction toward larger lymphatic vessels. 3. **Permeability:** The walls of lymphatic capillaries are highly permeable. This permeability is due to the loose connections between the endothelial cells, which allow not only interstitial fluid but also larger particles like proteins, cells, and pathogens to enter the capillary. 4. **Lack of Basement Membrane:** Unlike blood capillaries, lymphatic capillaries lack a continuous basement membrane. This absence of a barrier makes it easier for larger particles to enter the capillary. 5. **Interstitial Pressure:** The pressure in the interstitial space is higher than the pressure inside lymphatic capillaries. This pressure gradient encourages fluid and particles to enter the capillaries. 6. **Anchoring Filaments:** Lymphatic capillaries are anchored to surrounding tissues by thin filaments. These filaments help to keep the capillaries open, creating small openings for fluid and particles to flow in. Due to these characteristics, lymphatic capillaries can collect not only interstitial fluid but also various cells, proteins, pathogens, and other particles from the tissues. This collected material then becomes lymph, which is transported through the lymphatic system to perform its roles in maintaining fluid balance, immune response, and waste removal.

Work Step by Step

**Production of Lymph:** Lymph is derived from the interstitial fluid that surrounds cells in tissues. Interstitial fluid is the fluid that bathes the cells and provides them with nutrients and oxygen while removing waste products. As blood circulates through the capillaries, some of the plasma (the liquid component of blood) leaks out of the capillaries and into the surrounding tissues, forming interstitial fluid. This interstitial fluid is then collected by tiny, specialized vessels called lymphatic capillaries. These capillaries are part of the lymphatic system and are responsible for collecting the interstitial fluid and transforming it into lymph. The collected fluid, now referred to as lymph, is transported through larger lymphatic vessels and eventually reaches lymph nodes, where it undergoes filtration and processing before reentering the bloodstream. **Characteristics of Lymphatic Capillaries:** Lymphatic capillaries have unique characteristics that allow them to collect interstitial fluid, as well as cells and other particles, to form lymph. Here are some of the key characteristics: 1. **Structure:** Lymphatic capillaries have thin walls made of a single layer of endothelial cells, which are loosely connected. This structure creates small gaps or flaps between the cells that allow for easy entry of interstitial fluid. 2. **Valves:** Lymphatic capillaries have one-way valves that prevent the backflow of lymph once it enters the capillary. These valves ensure that once the fluid is inside, it moves in one direction toward larger lymphatic vessels. 3. **Permeability:** The walls of lymphatic capillaries are highly permeable. This permeability is due to the loose connections between the endothelial cells, which allow not only interstitial fluid but also larger particles like proteins, cells, and pathogens to enter the capillary. 4. **Lack of Basement Membrane:** Unlike blood capillaries, lymphatic capillaries lack a continuous basement membrane. This absence of a barrier makes it easier for larger particles to enter the capillary. 5. **Interstitial Pressure:** The pressure in the interstitial space is higher than the pressure inside lymphatic capillaries. This pressure gradient encourages fluid and particles to enter the capillaries. 6. **Anchoring Filaments:** Lymphatic capillaries are anchored to surrounding tissues by thin filaments. These filaments help to keep the capillaries open, creating small openings for fluid and particles to flow in. Due to these characteristics, lymphatic capillaries can collect not only interstitial fluid but also various cells, proteins, pathogens, and other particles from the tissues. This collected material then becomes lymph, which is transported through the lymphatic system to perform its roles in maintaining fluid balance, immune response, and waste removal.
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