Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 21 - Section 21.1 - Study Guide - Assess Your Learning Outcomes - Page 844: 11

Answer

**Structure of Red Bone Marrow:** Red bone marrow, also known as myeloid tissue, is a spongy tissue found within the cavities of certain bones in the human body. It is responsible for the production of blood cells through a process called hematopoiesis. The structure of red bone marrow is well-suited for its function: 1. **Cellular Composition:** Red bone marrow consists of a complex network of connective tissue, blood vessels, and various types of hematopoietic cells at different stages of development. 2. **Stromal Cells:** Specialized cells called stromal cells provide structural support for the hematopoietic cells. These cells produce the reticular fibers and extracellular matrix that form the framework of the marrow. 3. **Hematopoietic Cells:** The primary function of red bone marrow is to produce blood cells. Hematopoietic stem cells (HSCs) are the multipotent cells that give rise to all types of blood cells. HSCs differentiate into various progenitor cells, which then further differentiate into specific blood cell lineages, including red blood cells, white blood cells, and platelets. 4. **Sinusoids:** Red bone marrow contains a network of blood vessels called sinusoids. These sinusoids allow for the exchange of nutrients, oxygen, waste products, and newly formed blood cells between the bone marrow and the bloodstream. **Function of Red Bone Marrow:** The primary function of red bone marrow is hematopoiesis, which is the production and maturation of blood cells. This process ensures a constant supply of blood cells that are necessary for various physiological functions in the body: 1. **Red Blood Cells (Erythrocytes):** Erythropoiesis, the production of red blood cells, occurs in red bone marrow. Red blood cells transport oxygen from the lungs to body tissues and carry carbon dioxide from tissues back to the lungs for exhalation. 2. **White Blood Cells (Leukocytes):** White blood cells are integral components of the immune system. They are produced in red bone marrow and play roles in immune defense against infections, inflammation, and immune surveillance. 3. **Platelets (Thrombocytes):** Platelets are small cell fragments produced in red bone marrow. They are crucial for blood clotting, helping to prevent excessive bleeding when blood vessels are damaged. 4. **Hematopoietic Stem Cells (HSCs):** HSCs are the source of all blood cells. They have the unique ability to self-renew and differentiate into various cell lineages. HSCs ensure a continuous supply of blood cells throughout a person's lifetime. 5. **Immune Cell Differentiation:** Some types of white blood cells, including certain types of lymphocytes, undergo further differentiation and maturation in red bone marrow before being released into circulation. These cells are crucial for adaptive immune responses. Overall, red bone marrow is vital for maintaining the balance of blood cell populations, supporting immune function, and ensuring proper oxygen transport and blood clotting.

Work Step by Step

**Structure of Red Bone Marrow:** Red bone marrow, also known as myeloid tissue, is a spongy tissue found within the cavities of certain bones in the human body. It is responsible for the production of blood cells through a process called hematopoiesis. The structure of red bone marrow is well-suited for its function: 1. **Cellular Composition:** Red bone marrow consists of a complex network of connective tissue, blood vessels, and various types of hematopoietic cells at different stages of development. 2. **Stromal Cells:** Specialized cells called stromal cells provide structural support for the hematopoietic cells. These cells produce the reticular fibers and extracellular matrix that form the framework of the marrow. 3. **Hematopoietic Cells:** The primary function of red bone marrow is to produce blood cells. Hematopoietic stem cells (HSCs) are the multipotent cells that give rise to all types of blood cells. HSCs differentiate into various progenitor cells, which then further differentiate into specific blood cell lineages, including red blood cells, white blood cells, and platelets. 4. **Sinusoids:** Red bone marrow contains a network of blood vessels called sinusoids. These sinusoids allow for the exchange of nutrients, oxygen, waste products, and newly formed blood cells between the bone marrow and the bloodstream. **Function of Red Bone Marrow:** The primary function of red bone marrow is hematopoiesis, which is the production and maturation of blood cells. This process ensures a constant supply of blood cells that are necessary for various physiological functions in the body: 1. **Red Blood Cells (Erythrocytes):** Erythropoiesis, the production of red blood cells, occurs in red bone marrow. Red blood cells transport oxygen from the lungs to body tissues and carry carbon dioxide from tissues back to the lungs for exhalation. 2. **White Blood Cells (Leukocytes):** White blood cells are integral components of the immune system. They are produced in red bone marrow and play roles in immune defense against infections, inflammation, and immune surveillance. 3. **Platelets (Thrombocytes):** Platelets are small cell fragments produced in red bone marrow. They are crucial for blood clotting, helping to prevent excessive bleeding when blood vessels are damaged. 4. **Hematopoietic Stem Cells (HSCs):** HSCs are the source of all blood cells. They have the unique ability to self-renew and differentiate into various cell lineages. HSCs ensure a continuous supply of blood cells throughout a person's lifetime. 5. **Immune Cell Differentiation:** Some types of white blood cells, including certain types of lymphocytes, undergo further differentiation and maturation in red bone marrow before being released into circulation. These cells are crucial for adaptive immune responses. Overall, red bone marrow is vital for maintaining the balance of blood cell populations, supporting immune function, and ensuring proper oxygen transport and blood clotting.
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