Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 12 - Section 12.4 - Electrophysiology of Neurons - Before You Go On - Page 455: 17

Answer

Myelinated fibers conduct signals much faster than unmyelinated fibers due to the presence of the myelin sheath, which acts as an insulating layer around the axon. This insulation has several key effects that enhance the speed of signal conduction: 1. **Saltatory Conduction:** In myelinated fibers, the myelin sheath covers segments of the axon with small gaps in between called "Nodes of Ranvier." At these nodes, the axon membrane is exposed. Action potentials can only be generated at the nodes, not along the myelinated segments. This results in a process called "saltatory conduction," where the action potential "jumps" from one node to the next, bypassing the myelinated regions. 2. **Reduced Capacitance:** Myelin is an insulator, and it prevents ions from leaking across the axon membrane. This reduces the capacitance of the axon, meaning that the axon can hold its charge better. In unmyelinated axons, the capacitance is higher, and charge leakage is more significant, requiring more energy to maintain the electrical signal. Myelinated axons conserve energy by minimizing ion leakage. 3. **Faster Axonal Membrane Depolarization:** At the nodes of Ranvier, where the axonal membrane is exposed, ion channels necessary for generating action potentials are densely concentrated. When an action potential is initiated at one node, it can propagate rapidly to the next node because there is no myelin to impede ion movement. This ensures fast and efficient depolarization of the axonal membrane at each node. 4. **Efficient Ionic Flow:** In myelinated axons, the movement of ions (particularly sodium and potassium) during the action potential is restricted to the nodes of Ranvier. This focused ionic flow accelerates the depolarization and repolarization of the membrane at the nodes, allowing for rapid signal transmission. 5. **Decreased Time Constant:** The time constant of an axon, which determines how quickly it responds to changes in membrane potential, is reduced in myelinated fibers. This means that the membrane potential changes more quickly in response to a stimulus, resulting in faster signal transmission. In summary, myelinated fibers conduct signals faster than unmyelinated fibers because myelin sheaths enable saltatory conduction, reduce capacitance, concentrate ion channels at nodes of Ranvier, facilitate efficient ionic flow, and decrease the time constant. These adaptations collectively enhance the speed and efficiency of signal propagation along myelinated axons, making them well-suited for rapid long-distance communication in the nervous system.

Work Step by Step

Myelinated fibers conduct signals much faster than unmyelinated fibers due to the presence of the myelin sheath, which acts as an insulating layer around the axon. This insulation has several key effects that enhance the speed of signal conduction: 1. **Saltatory Conduction:** In myelinated fibers, the myelin sheath covers segments of the axon with small gaps in between called "Nodes of Ranvier." At these nodes, the axon membrane is exposed. Action potentials can only be generated at the nodes, not along the myelinated segments. This results in a process called "saltatory conduction," where the action potential "jumps" from one node to the next, bypassing the myelinated regions. 2. **Reduced Capacitance:** Myelin is an insulator, and it prevents ions from leaking across the axon membrane. This reduces the capacitance of the axon, meaning that the axon can hold its charge better. In unmyelinated axons, the capacitance is higher, and charge leakage is more significant, requiring more energy to maintain the electrical signal. Myelinated axons conserve energy by minimizing ion leakage. 3. **Faster Axonal Membrane Depolarization:** At the nodes of Ranvier, where the axonal membrane is exposed, ion channels necessary for generating action potentials are densely concentrated. When an action potential is initiated at one node, it can propagate rapidly to the next node because there is no myelin to impede ion movement. This ensures fast and efficient depolarization of the axonal membrane at each node. 4. **Efficient Ionic Flow:** In myelinated axons, the movement of ions (particularly sodium and potassium) during the action potential is restricted to the nodes of Ranvier. This focused ionic flow accelerates the depolarization and repolarization of the membrane at the nodes, allowing for rapid signal transmission. 5. **Decreased Time Constant:** The time constant of an axon, which determines how quickly it responds to changes in membrane potential, is reduced in myelinated fibers. This means that the membrane potential changes more quickly in response to a stimulus, resulting in faster signal transmission. In summary, myelinated fibers conduct signals faster than unmyelinated fibers because myelin sheaths enable saltatory conduction, reduce capacitance, concentrate ion channels at nodes of Ranvier, facilitate efficient ionic flow, and decrease the time constant. These adaptations collectively enhance the speed and efficiency of signal propagation along myelinated axons, making them well-suited for rapid long-distance communication in the nervous system.
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