Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 12 - Section 12.4 - Electrophysiology of Neurons - Before You Go On - Page 455: 16

Answer

Action potentials and local potentials are two types of electrical signals in neurons, and they differ in several ways. Here are four key differences between them: 1. **Propagation Distance:** - **Action Potential:** Action potentials are all-or-nothing events that can propagate over long distances along the axon of a neuron. They travel without significant decay in amplitude. - **Local Potential:** Local potentials, also known as graded potentials, are subthreshold changes in membrane potential that occur in response to neurotransmitter binding or other stimuli. They are typically short-lived and decay with distance, making them non-propagating. 2. **Amplitude and Strength:** - **Action Potential:** Action potentials have a fixed, all-or-nothing amplitude. They reach a peak value (e.g., +35 mV in neurons) and do not vary in size, regardless of the strength of the stimulus. - **Local Potential:** Local potentials vary in amplitude depending on the strength of the stimulus. Stronger stimuli result in larger depolarizations, while weaker stimuli produce smaller depolarizations. 3. **Threshold and Initiation:** - **Action Potential:** Action potentials have a threshold level (around -55 to -50 mV in neurons) that must be reached to initiate them. Once the threshold is reached, the action potential is triggered and proceeds with a fixed amplitude and duration. - **Local Potential:** Local potentials do not have a threshold in the same way as action potentials. They can occur in response to any subthreshold change in membrane potential and do not necessarily lead to an action potential. 4. **All-or-Nothing vs. Graded:** - **Action Potential:** Action potentials are all-or-nothing events. Once initiated, they proceed to completion with a fixed amplitude and duration. There are no "partial" action potentials. - **Local Potential:** Local potentials are graded, meaning that their amplitude varies based on the strength of the stimulus. They can be small, medium, or large, depending on the input, and they do not always lead to an action potential. In summary, action potentials are distinct from local potentials in terms of their propagation, fixed amplitude, threshold, and all-or-nothing nature. Local potentials, on the other hand, are graded, short-lived, and can vary in amplitude depending on the strength of the stimulus.

Work Step by Step

Action potentials and local potentials are two types of electrical signals in neurons, and they differ in several ways. Here are four key differences between them: 1. **Propagation Distance:** - **Action Potential:** Action potentials are all-or-nothing events that can propagate over long distances along the axon of a neuron. They travel without significant decay in amplitude. - **Local Potential:** Local potentials, also known as graded potentials, are subthreshold changes in membrane potential that occur in response to neurotransmitter binding or other stimuli. They are typically short-lived and decay with distance, making them non-propagating. 2. **Amplitude and Strength:** - **Action Potential:** Action potentials have a fixed, all-or-nothing amplitude. They reach a peak value (e.g., +35 mV in neurons) and do not vary in size, regardless of the strength of the stimulus. - **Local Potential:** Local potentials vary in amplitude depending on the strength of the stimulus. Stronger stimuli result in larger depolarizations, while weaker stimuli produce smaller depolarizations. 3. **Threshold and Initiation:** - **Action Potential:** Action potentials have a threshold level (around -55 to -50 mV in neurons) that must be reached to initiate them. Once the threshold is reached, the action potential is triggered and proceeds with a fixed amplitude and duration. - **Local Potential:** Local potentials do not have a threshold in the same way as action potentials. They can occur in response to any subthreshold change in membrane potential and do not necessarily lead to an action potential. 4. **All-or-Nothing vs. Graded:** - **Action Potential:** Action potentials are all-or-nothing events. Once initiated, they proceed to completion with a fixed amplitude and duration. There are no "partial" action potentials. - **Local Potential:** Local potentials are graded, meaning that their amplitude varies based on the strength of the stimulus. They can be small, medium, or large, depending on the input, and they do not always lead to an action potential. In summary, action potentials are distinct from local potentials in terms of their propagation, fixed amplitude, threshold, and all-or-nothing nature. Local potentials, on the other hand, are graded, short-lived, and can vary in amplitude depending on the strength of the stimulus.
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