Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 12 - Section 12.2 - Properties of Neurons - Apply What You Know - Page 441: 1

Answer

The dense cytoskeleton of a neuron, primarily composed of microtubules, microfilaments, and neurofilaments, plays a crucial role in maintaining the structure and function of neurons. Here are two reasons why the dense cytoskeleton is important for neuron structure and function: 1. **Structural Support and Shape Maintenance:** The cytoskeleton provides essential structural support to the neuron. Microtubules, in particular, help maintain the shape of the neuron by serving as a rigid scaffold along the length of the axon. This is crucial for the proper functioning of neurons, especially those with long axons that need to transmit electrical signals over long distances. Without a stable cytoskeleton, neurons might lose their structural integrity, leading to misshapen or compromised axons, which could disrupt signal propagation. 2. **Axonal Transport:** Neurons have specialized transport processes for moving essential molecules and organelles between the cell body and the axon terminals. This intracellular transport, often called axonal transport, is facilitated by molecular motors like kinesins and dyneins that move along the microtubules of the cytoskeleton. These motors transport vital materials such as neurotransmitter vesicles, mitochondria, and proteins to and from the synapses. The cytoskeleton, especially microtubules, provides tracks for these motor proteins to travel on, allowing efficient and directional transport. Without a well-organized cytoskeleton, axonal transport would be disrupted, impairing the neuron's ability to communicate and function properly. In summary, the dense cytoskeleton of a neuron is essential for maintaining its structural integrity, ensuring proper axonal transport, and ultimately enabling the neuron to function effectively in transmitting signals within the nervous system.

Work Step by Step

The dense cytoskeleton of a neuron, primarily composed of microtubules, microfilaments, and neurofilaments, plays a crucial role in maintaining the structure and function of neurons. Here are two reasons why the dense cytoskeleton is important for neuron structure and function: 1. **Structural Support and Shape Maintenance:** The cytoskeleton provides essential structural support to the neuron. Microtubules, in particular, help maintain the shape of the neuron by serving as a rigid scaffold along the length of the axon. This is crucial for the proper functioning of neurons, especially those with long axons that need to transmit electrical signals over long distances. Without a stable cytoskeleton, neurons might lose their structural integrity, leading to misshapen or compromised axons, which could disrupt signal propagation. 2. **Axonal Transport:** Neurons have specialized transport processes for moving essential molecules and organelles between the cell body and the axon terminals. This intracellular transport, often called axonal transport, is facilitated by molecular motors like kinesins and dyneins that move along the microtubules of the cytoskeleton. These motors transport vital materials such as neurotransmitter vesicles, mitochondria, and proteins to and from the synapses. The cytoskeleton, especially microtubules, provides tracks for these motor proteins to travel on, allowing efficient and directional transport. Without a well-organized cytoskeleton, axonal transport would be disrupted, impairing the neuron's ability to communicate and function properly. In summary, the dense cytoskeleton of a neuron is essential for maintaining its structural integrity, ensuring proper axonal transport, and ultimately enabling the neuron to function effectively in transmitting signals within the nervous system.
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