Answer
$59$
Work Step by Step
Solve using PEMDAS (The priority list for solving expressions: Parentheses, exponents, [multiplication, division], [addition, subtraction]. For the operations in the brackets, solve from left to right)
$2^4\cdot 4 - (25 \div 5) = 2^4\cdot 4 - 5 = 16\cdot 4-5 = 64-5 = 59$