One Hundred Years of Solitude is the story of seven generations of the Buendía Family in the town of Macondo. The founding patriarch of Macondo, José Arcadio Buendía, and Úrsula Iguarán, his wife (and first cousin), leave Riohacha, Colombia, to find a better life and a new home. One night of their emigration journey, while camping on a riverbank, José Arcadio Buendía dreams of "Macondo", a city of mirrors that reflected the world in and about it. Upon awakening, he decides to establish Macondo at the river side; after days of wandering the jungle, José Arcadio Buendía's founding of Macondo is utopic.
Founding patriarch José Arcadio Buendía believes Macondo to be surrounded by water, and from that island, he invents the world according to his perceptions. Soon after its foundation, Macondo becomes a town frequented by unusual and extraordinary events that involve the generations of the Buendía family, who are unable or unwilling to escape their periodic (mostly self-inflicted) misfortunes. Ultimately, a hurricane destroys Macondo, the city of mirrors; just the cyclical turmoil inherent to Macondo. At the end of the story, a Buendía man deciphers an encryption that generations of Buendía family men had failed to decode. The secret message informed the recipient of every fortune and misfortune lived by the Buendía Family generations.