The novel covers Miller's growing inability and outright refusal to accommodate what he sees as America's hostile environment. It is autobiographical but not chronological, jumping between Miller's adolescent adventures in Brooklyn in the 1900s, recollections of his first love Una Gifford, a love affair with his nearly 30-year-old piano teacher when he was 15, his unhappy marriage to his first wife Beatrice, his years working at Western Union (called The Cosmodemonic Telegraph Company in the book) in Manhattan in the 1920s, and his fateful meeting with his second wife June (known in the book as Mara), whom he credits with changing his life and making him into a writer.
The Rosy Crucifixion continues the story of June in greater detail, over the course of nearly 1,500 pages. It describes the process of Miller finding his voice as a writer, until eventually he sets off for Paris, where the activities depicted in Tropic of Cancer begin.[16][17][18][19]