Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 21 - Section 21.3 - Study Guide - Assess Your Learning Outcomes - Page 844: 4

Answer

An antigen is a molecule or molecular structure that is recognized by the immune system as foreign and capable of triggering an immune response. Antigens can be proteins, polysaccharides, lipids, nucleic acids, or even small molecules. When the immune system encounters an antigen, it generates a specific response to neutralize or eliminate it. The chemical characteristics of antigens include: 1. **Foreignness:** Antigens are typically substances that are not naturally present in the body. They are recognized by the immune system as non-self, which distinguishes them from the body's own components. 2. **Complexity:** Antigens are often complex molecules or molecular structures. These can include proteins with intricate folding patterns, carbohydrates with specific branching arrangements, and more. The complexity contributes to the specificity of the immune response. 3. **Specificity:** Antigens are recognized by the immune system through specific molecular interactions. Immune cells have receptors that can bind to specific antigenic epitopes (small regions of the antigen). This interaction is highly specific, allowing the immune system to distinguish between different antigens. 4. **Immunogenicity:** Not all molecules can serve as antigens. Antigens need to possess sufficient immunogenicity, which means they can stimulate an immune response. This often involves the activation of immune cells and the production of antibodies against the antigen. 5. **Molecular Size:** Antigens can vary in size, ranging from small molecules like drugs or haptens to large macromolecules like proteins. The size of the antigen can affect how it interacts with immune cells and the strength of the immune response. 6. **Variability:** Antigens can have different variations or forms. For example, pathogens can mutate their surface antigens to evade the immune system. This variability can pose challenges for the immune response to maintain recognition. 7. **Cross-Reactivity:** Some antigens may share similar structural features, leading to cross-reactivity. This means that an immune response generated against one antigen can also target a different, but structurally similar, antigen. 8. **Heterogeneity:** In complex organisms, such as humans, there are numerous potential antigens due to the diversity of proteins, carbohydrates, and other molecules. Each individual can have a unique set of antigens based on their genetic makeup and exposure to environmental factors. In summary, antigens are foreign molecules that trigger an immune response. They exhibit various chemical characteristics, including their foreign nature, complexity, specificity, immunogenicity, and variability, all of which contribute to the immune system's ability to detect and respond to potential threats.

Work Step by Step

An antigen is a molecule or molecular structure that is recognized by the immune system as foreign and capable of triggering an immune response. Antigens can be proteins, polysaccharides, lipids, nucleic acids, or even small molecules. When the immune system encounters an antigen, it generates a specific response to neutralize or eliminate it. The chemical characteristics of antigens include: 1. **Foreignness:** Antigens are typically substances that are not naturally present in the body. They are recognized by the immune system as non-self, which distinguishes them from the body's own components. 2. **Complexity:** Antigens are often complex molecules or molecular structures. These can include proteins with intricate folding patterns, carbohydrates with specific branching arrangements, and more. The complexity contributes to the specificity of the immune response. 3. **Specificity:** Antigens are recognized by the immune system through specific molecular interactions. Immune cells have receptors that can bind to specific antigenic epitopes (small regions of the antigen). This interaction is highly specific, allowing the immune system to distinguish between different antigens. 4. **Immunogenicity:** Not all molecules can serve as antigens. Antigens need to possess sufficient immunogenicity, which means they can stimulate an immune response. This often involves the activation of immune cells and the production of antibodies against the antigen. 5. **Molecular Size:** Antigens can vary in size, ranging from small molecules like drugs or haptens to large macromolecules like proteins. The size of the antigen can affect how it interacts with immune cells and the strength of the immune response. 6. **Variability:** Antigens can have different variations or forms. For example, pathogens can mutate their surface antigens to evade the immune system. This variability can pose challenges for the immune response to maintain recognition. 7. **Cross-Reactivity:** Some antigens may share similar structural features, leading to cross-reactivity. This means that an immune response generated against one antigen can also target a different, but structurally similar, antigen. 8. **Heterogeneity:** In complex organisms, such as humans, there are numerous potential antigens due to the diversity of proteins, carbohydrates, and other molecules. Each individual can have a unique set of antigens based on their genetic makeup and exposure to environmental factors. In summary, antigens are foreign molecules that trigger an immune response. They exhibit various chemical characteristics, including their foreign nature, complexity, specificity, immunogenicity, and variability, all of which contribute to the immune system's ability to detect and respond to potential threats.
Update this answer!

You can help us out by revising, improving and updating this answer.

Update this answer

After you claim an answer you’ll have 24 hours to send in a draft. An editor will review the submission and either publish your submission or provide feedback.