Chapter 17 - Section 17.6 - Eicosanoids and Paracrine Signaling - Before You Go On - Page 661: 26

Paracrine Effect: A paracrine effect refers to a mode of cell-to-cell communication where signaling molecules are released by one cell and act on neighboring cells within the immediate vicinity of the release site. In other words, the signaling molecules affect nearby cells without entering the bloodstream. Paracrine signaling is important for coordinating and regulating processes within local tissues. An example of a paracrine effect is the release of neurotransmitters by nerve cells, which affect adjacent nerve cells or target cells in close proximity. Endocrine Effect: An endocrine effect, on the other hand, involves the release of signaling molecules (hormones) into the bloodstream by specialized glands called endocrine glands. These hormones then travel through the bloodstream to reach distant target cells or organs equipped with specific receptors for those hormones. The target cells may be located far away from the site of hormone release. Endocrine signaling is crucial for regulating processes that require coordination throughout the entire body, such as growth, metabolism, and reproduction. In summary: - Paracrine Effect: Signaling molecules released by one cell affect nearby cells in the immediate vicinity without entering the bloodstream. This local signaling is important for coordinating responses within tissues. - Endocrine Effect: Signaling molecules (hormones) are released into the bloodstream by endocrine glands and travel to distant target cells or organs with specific receptors. This systemic signaling coordinates processes that require communication throughout the entire body.

Paracrine Effect: A paracrine effect refers to a mode of cell-to-cell communication where signaling molecules are released by one cell and act on neighboring cells within the immediate vicinity of the release site. In other words, the signaling molecules affect nearby cells without entering the bloodstream. Paracrine signaling is important for coordinating and regulating processes within local tissues. An example of a paracrine effect is the release of neurotransmitters by nerve cells, which affect adjacent nerve cells or target cells in close proximity. Endocrine Effect: An endocrine effect, on the other hand, involves the release of signaling molecules (hormones) into the bloodstream by specialized glands called endocrine glands. These hormones then travel through the bloodstream to reach distant target cells or organs equipped with specific receptors for those hormones. The target cells may be located far away from the site of hormone release. Endocrine signaling is crucial for regulating processes that require coordination throughout the entire body, such as growth, metabolism, and reproduction. In summary: - Paracrine Effect: Signaling molecules released by one cell affect nearby cells in the immediate vicinity without entering the bloodstream. This local signaling is important for coordinating responses within tissues. - Endocrine Effect: Signaling molecules (hormones) are released into the bloodstream by endocrine glands and travel to distant target cells or organs with specific receptors. This systemic signaling coordinates processes that require communication throughout the entire body.