Anatomy & Physiology: The Unity of Form and Function, 7th Edition

Published by McGraw-Hill Education
ISBN 10: 0073403717
ISBN 13: 978-0-07340-371-7

Chapter 12 - Section 12.6 - Figure 12.24 - Postsynaptic Potentials - Page 462: 1

Answer

A single EPSP has a voltage of only about 0.5 mV. (.03 to 6 mV). Threshold for most neurons is about -55 mV which can only be reached by application of a stimulus voltage of at least 15 mV. The voltage of a single EPSP is therefore too small (low) to trigger an action potential.

Work Step by Step

The resting potential of neurons is about -70 mV. Since threshold is about -55 mV, a stimulus must be about +15 mV to trigger an action potential (AP). The voltage of an individual EPSP is much to small to trigger an AP.
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