Answer
$-18$
Work Step by Step
Follow the order of operations, "Parentheses, Exponents, Multiplication and Division, and Addition and Subtraction". Keep in mind that after completing everything inside the brackets, replace the brackets with parentheses, and complete everything inside those first as well.
$-5+[(4-15)-(-6)-8]=-5+(-11+6-8)=-5+(-13)=-18$