- Antiochus – king of Antioch
- Pericles – Prince of Tyre
- Helicanus and Escanes – two lords of Tyre
- Simonides – king of Pentapolis
- Cleon – governor of Tarsus
- Lysimachus – governor of Mytilene
- Cerimon – a lord of Ephesus
- Thaliard – a lord of Antioch
- Philemon – servant to Cerimon
- Leonine – servant to Dionyza
- Marshal
- A Pandar (male owner of a brothel)
- Boult – The Pandar's servant
- The Daughter of Antiochus
- Dionyza – wife to Cleon
- Thaisa – daughter to Simonides, Pericles' wife
- Marina – daughter to Pericles and Thaisa
- Lychorida – nurse to Marina
- A Bawd (female owner of a brothel)
- Diana
- Gower as Chorus
- Lords, Knights, Gentlemen, Sailors, Pirates, Fisherman, and Messengers
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