- A film adaptation, Perfume: The Story of a Murderer, co-written and directed by Tom Tykwer (who also composed the film score), premiered in Germany on 14 September 2006.
- A Russian musical adaptation of the novel, Perfumer, premiered on 5 December 2010 in Moscow. Composer and singer Igor Demarin received Süskind's approval after communicating with a representative of his for two years.
- The song "Scentless Apprentice", by the American grunge band Nirvana, was inspired by Perfume. It appears on their 1993 album In Utero. The band's singer and guitarist Kurt Cobain often described the novel as one of his favourite books, in an interview on August 10th 1993 in Seattle, Washington.
- The song "Herr Spiegelmann" from the Portuguese gothic-doom metal band Moonspell contains an excerpt from the book.
- The song "Red Head Girl" by French downtempo duo Air is inspired by Perfume.
- The song "Du riechst so gut" (German for "You smell so good") by Rammstein was inspired by the book, which is one of lead singer Till Lindemann's favourite books.
- Marilyn Manson credits the novel as one of the inspirations behind the title of his second album, Smells Like Children.
- The episode "Sense Memory" of the television show Criminal Minds bears many similarities to the novel.
- The song "Nearly Witches (Ever Since We Met)" by Panic! at the Disco is inspired by Perfume.
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