The work has received a multitude of citations and references from subsequent philosophical books as well as literary articles, works of fiction, and the like. On the Genealogy of Morality is considered by many academics to be Nietzsche's most important work, and, despite its polemical style, out of all of his works the one that perhaps comes closest to a systematic and sustained exposition of his ideas. Some of the contents and many symbols and metaphors portrayed in On the Genealogy of Morality, together with its tripartite structure, seem to be based on and influenced by Heinrich Heine's On the History of Religion and Philosophy in Germany.
In philosophy, the genealogical method is a historical technique in which one questions the commonly understood emergence of various philosophical and social beliefs by attempting to account for the scope, breadth or totality of ideology within the time period in question, as opposed to focusing on a singular or dominant ideology. In epistemology, it has been first used by Nietzsche and later by Michel Foucault, who tried to expand and apply the concept of genealogy as a novel method of research in sociology (evinced principally in "histories" of sexuality and punishment). In this aspect Foucault was heavily influenced by Nietzsche.
Others have adapted "genealogy" in a looser sense to inform their work. An example is the attempt by the British philosopher Bernard Williams to vindicate the value of truthfulness using lines of argument derived from genealogy in his book Truth and Truthfulness (2002). Daniel Dennett wrote that On The Genealogy of Morality is "one of the first and still subtlest of the Darwinian investigations of the evolution of ethics". Stephen Greenblatt has said in an interview that On The Genealogy of Morality was the most important influence on his life and work.
The book is referenced and discussed in Pier Paolo Pasolini's 1975 film Salò, or the 120 Days of Sodom.