The film's original score was composed for a large orchestra by Gottfried Huppertz. Huppertz drew inspiration from Richard Wagner and Richard Strauss, and combined a classical orchestral voice with mild modernist touches to portray the film's massive industrial city of workers. Nestled within the original score were quotations of Claude Joseph Rouget de Lisle's "La Marseillaise" and the traditional "Dies Irae," the latter of which was matched to the film's apocalyptic imagery. Huppertz's music played a prominent role during the film's production; oftentimes, the composer played piano on Lang's set in order to inform the actors' performances.
The score was rerecorded for the 2001 DVD release of the film with Berndt Heller conducting the Rundfunksinfonieorchester Saarbrücken. It was the first release of the reasonably reconstructed movie to be accompanied by Huppertz's original score. In 2007, Huppertz's score was also played live by the VCS Radio Symphony, which accompanied the restored version of the film at Brenden Theatres in Vacaville, California. The score was also produced in a salon orchestration, which was performed for the first time in the United States in August 2007 by The Bijou Orchestra under the direction of Leo Najar as part of a German Expressionist film festival in Bay City, Michigan. The same forces also performed the work at the Traverse City Film Festival in Traverse City, Michigan in August 2009.
For the 2010 reconstruction DVD, the score was performed and recorded by the Berlin Radio Symphony Orchestra, conducted by Frank Strobel. Strobel also conducted the premiere of the reconstructed score at Berlin Friedrichstadtpalast.
There have been many other soundtracks created for Metropolis by different artists. In 1975, the BBC provided a electronic score composed by William Fitzwater and Hugh Davies. In 1984 Giorgio Moroder restored and produced the 80-minute 1984 re-release, which had a pop soundtrack written by Moroder and performed by Moroder, Pat Benatar, Bonnie Tyler, Jon Anderson, Adam Ant, Cycle V, Loverboy, Billy Squier, and Freddie Mercury. In 1991 the Club Foot Orchestra created an original score that was performed live with the film. It was also recorded for CD. In 1994, Montenegrin experimental rock musician Rambo Amadeus wrote his version of the musical score for Metropolis. At the screening of the film in Belgrade, the score was played by the Belgrade Philharmonic Orchestra. In 1998, the material was recorded and released on the album Metropolis B (tour-de-force). In 1996 the Degenerate Art Ensemble (then The Young Composers Collective) scored the film for chamber orchestra, performing it in various venues including a free outdoor concert and screening in 1997 in Seattle's Gasworks Park. The soundtrack was subsequently released on Un-Labeled Records. In 2000, Jeff Mills created a techno score for Metropolis which was released as an album. He also performed the score live at public screenings of the film. In 2004 Abel Korzeniowski created a score for Metropolis played live by a 90-piece orchestra and a choir of 60 voices and two soloists. The first performance took place at the Era Nowe Horyzonty Film Festival in Poland. The same year, Ronnie Cramer produced a score and effects soundtrack for Metropolis that won two Aurora awards. The New Pollutants (Mister Speed and DJ Tr!p) has performed Metropolis Rescore live for festivals since 2005 and are rescoring to the 2010 version of the film for premiere at the 2011 Adelaide Film Festival. In 2010, the Alloy Orchestra has scored four different versions of the film, most recently for the American premiere of the 2010 restoration. In 2014 the pianist/composer, Dmytro Morykit, created a new live piano score which received a standing ovation to a sell-out audience at Wilton's Music Hall in London.