- Rigaud: European man who is in prison in Marseilles awaiting trial for murdering his wife. He demands that others treat him as a gentleman, though he does not treat others as a gentleman would. After he persuades the jury he is not guilty, he is known as Lagnier when encountered by Cavalletto at an inn in France. In England he is known as Blandois.
- John Baptist Cavalletto: Italian man awaiting trial for minor smuggling in Marseilles and put in the same cell with Rigaud. He makes his way to England, settling in Bleeding Heart Yard, through his connection with Arthur Clennam.
- Arthur Clennam: Returning from China, he spent weeks in quarantine in Marseilles, having traveled through a place with plague. He is 40 years old single, and meets new friends in the quarantine. He is a man of honour and kindness, with skills in business.
- Mrs Clennam: Wife of Arthur Clennam's father, who ran the family business in London. She was raised in a strict and harsh religious sect and keeps up the ways of her childhood. She kept Arthur with her in London until he was caught with a girlfriend, and both she and the girl's parents disapproved of the connection. She sent him away to work with his father in China.
- Mr Gilbert Clennam: Uncle to the father of Arthur Clennam and founder of the family business. He forced Arthur's father, whom he raised, to give up the marriage he made to marry a woman of the uncle's choosing. Gilbert Clennam is not alive in the time of this story but was when Arthur was born 40 years earlier.
- The biological mother of Arthur Clennam: She is only mentioned as Arthur's biological mother and the first wife of his father. She was pushed away by Mrs Clennam and Gilbert Clennam.
- Affery: Later Mrs Flintwinch. She takes care of Mrs Clennam and of Arthur before he went to China. She is afraid of both her husband and her mistress. She hears the sounds of the building, all mysterious to her.
- Mr Jeremiah Flintwinch: Clerk to the Clennam business until Arthur announces that he will not work in the family business on his return to London. Mr Flintwinch is raised up to be partner with Mrs Clennam. When Mrs Clennam became an invalid needing much care, she decided that Flintwinch and Affery should marry, so they did. After the blackmail attempt, he fled London and was said to be known as Mynheer von Flyntevynge in Amsterdam and The Hague.
- Mr Meagles: A retired English banker travelling in Europe with his wife, daughter and the maid for his daughter. He and his family are held in quarantine at Marseilles, having travelled through an area with plague, though none are ill. He becomes friends with Arthur Clennam.
- Mrs Meagles: Wife of Mr Meagles and mother of their daughter.
- Minnie Meagles: Daughter of Mr and Mrs Meagles, survivor of twin girls. She is a beautiful young woman, spoiled by her parents, and known as Pet to them.
- Tattycoram: Maid to Minnie Meagles. She was an orphan taken in by the Meagles. She is younger than Minnie, with rich dark hair, and has a temperament that can run to anger. Her real name is Harriet Beadle. She lives with the family in Twickenham, then with Miss Wade in London and in Calais until she returns to the Meagles.
- Miss Wade: Another traveller held in quarantine in Marseilles. She is aloof but makes a connection with Tattycoram. She once was wooed by Henry Gowan. She is linked with Rigaud, as he left the valuable box of Clennam family papers with her.
- Mr William Dorrit: About thirty years before the story begins, he entered the Marshalsea debtors' prison with his wife and two children. Over time he becomes the "Father of the Marshalsea", based on his social ways, maintaining the expectations of the class in which he was raised. He makes no efforts to resolve the situation that put him in the prison.
- Mrs Dorrit: She arrived at the prison a day after her husband, with their two children. She was pregnant, and about seven months later gave birth to their third child and second daughter. Mrs Dorrit died when the girl was about 8 years old.
- Edward Dorrit: The eldest child of the Dorrits, also called Tip, who enters the prison at about age 3. He grows up to become a gambler.
- Fanny Dorrit: The elder daughter of the Dorrits, who enters the prison at age 2. She grows to be an attractive and active young woman, who takes training in dancing for the theatre. Later she marries Edmund Sparkler.
- Amy Dorrit: She was born in the prison and is called Little Dorrit. She grows up as a girl who cares for others and is practical in getting enough money to support herself and her father in the prison. She is the emotional and practical centre of her family. She is 22 years old when the story opens.
- Frederick Dorrit: Elder brother of William, uncle to Edward, Fanny and Amy. He is artistic, and he plays a musical instrument to support himself since the family finances fell apart. He does not have the same character as his younger brother. In his younger days, he had a house for artistic people, and took in the mother of Arthur Clennam who was a singer.
- Young John Chivery: He is the son of John Chivery, who hopes to hand over his position on the lock at the Marshalsea Prison in due time. Young John is in love with Little Dorrit, but his feelings are not returned. He acts to aid her when he can, including helping Pancks in the "fortune teller" task of linking the Dorrits to their inheritance.
- Mrs Finching: Now a widow, in her young days Flora was in love with Arthur Clennam. When he returns to England, she maintains a hope that he will fall in love with her again, though she has changed greatly. She adds humour when she enters a scene, never able to address Arthur as Mr Clennam, as would be proper in the present. Her father is Mr Casby.
- Mr F's aunt: When her husband dies, Mrs Finching inherits the care of his aunt, whose words are spoken with defiance, but never really make sense.
- Mr Christopher Casby: Also called The Patriarch, for his deceptively kind appearance, with long grey hair. He pushes Pancks to ruthlessly collect rents, while maintaining a benevolent image before the world. He owns the property of Bleeding Heart Yard, and Flora is his daughter.
- Mr Pancks: Rent collector for Mr Casby. He becomes friends with Arthur Clennam, and indulges his side interest of matching people with lost inheritances, in which role he calls himself the "fortune teller".
- Mr Rugg: Attorney for Mr Pancks and for Doyce & Clennam, also landlord to Pancks. He aided in the "fortune-telling" work to link Dorrits to their inheritance.
- Daniel Doyce: An inventor of mechanical devices, with a trail of successes in Paris and St Petersburg. He returns to England with vain hopes of getting a patent on a device he invented, and he has a company based in Bleeding Heart Yard. He first meets Arthur Clennam in the Circumlocution Department. He is friends with Mr Meagles, and takes on Arthur Clennam as his man of finance and business partner.
- Mr Edmund Sparkler: A dimwitted, upper class, young man who falls for Fanny Dorrit as a dancer. They meet again when the Dorrits are wealthy, and he pursues Fanny until she agrees to marry him. Before Mr Merdle (his "governor") fails, he secures a position for Sparkler in the Circumlocution Office.
- Mrs Merdle: Mother of Edmund Sparkler, and remarried to Mr Merdle. She finds her social match in Fanny Dorrit. She is also referred to as 'the Bosom'.
- Mr Merdle: In the period of riches for the Dorrits, he is the "man of the age", a banker and financier. News of his success in investments spreads like wildfire, with everyone putting their money with him, or wishing they could. His schemes fail, which is learned after he commits suicide.
- Mr Henry Gowan: Handsome young man, related to the Barnacle family but not closely enough to have more than a small annual income from his mother. He is earns money as an artist, pursues Minnie Meagles and marries her around the time that the Dorrits become rich. He is supported financially by his in-laws. The young couple meet the Dorrits while both are touring in Europe.
- Mr Tite Barnacle: On staff in the Circumlocution Department in London. He is part of the titled family, the Barnacles. Arthur encounters him in his persistence, first to learn the creditor who keeps William Dorrit in debtors' prison, then to get the patent for Doyce's invention, two unsuccessful ventures.
- Mr Ferdinand Barnacle: Younger member of the noble family and friends with Henry Gowan. He visits Arthur Clennam at the Marshalsea prison, happy to learn the Circumlocution Office did not put him into the debtors' prison, and tries to explain to Arthur the value of their office doing nothing.
- Mr Plornish: Plasterer who lives with his family in Bleeding Heart Yard. He was briefly in the Marshalsea prison, where he met William Dorrit and Little Dorrit. He is a friend to Little Dorrit. Later he and his wife have a store, with funds supplied by William Dorrit before he left England.
- Mrs Plornish: Wife of the plasterer and a good friend to John Baptist Cavalletto when he arrives in Bleeding Heart Yard and a friend to Arthur Clennam.
- Mr Nandy: Father of Mrs Plornish. He lives with his daughter's family when their finances improve. Otherwise, he is forced to live in the poorhouse. He is the one pauper whom William Dorrit allows to visit him, but when Little Dorrit walks with him from the Plornish home to the prison, Dorrit is enraged that she is seen on the streets with a pauper.
- Maggy: Young woman, left underdeveloped due to disease, who is befriended by Little Dorrit. She calls Little Dorrit her little mother, as Maggy is taller and bigger than Little Dorrit.
- Mrs General: Widow hired by William Dorrit to guide his daughters in the ways of society when the family is rich. She is proud never to show any feelings, and always speak calmly. She is well "varnished".
- Ephraim Flintwinch: Twin brother of Jeremiah, living in Antwerp. He took in Arthur's birth mother after Mrs Clennam forced her away, and took care of her until her death, about the time that Arthur went off with his father. Before Arthur's return, Jeremiah gave his twin brother the original papers regarding the uncle's will and letters written by the mother. Rigaud murders Ephraim to obtain the box of documents.
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