Nemerov's work is formalist. He wrote almost exclusively in fixed forms and meter. While he is known for his meticulousness and refined technique, his work also has a reputation for being witty and playful. He is compared to John Hollander and Philip Larkin.
"A Primer of the Daily Round" is his most frequently anthologized poem, and highly representative of Nemerov's poetic style. It is an archetypal Elizabethan sonnet, demonstrative of the prosodic creativity for which Nemerov is famous. Another widely appreciated poem is "The War in the Air," which draws on his wartime experience as a pilot.
Nemerov's "Because You Asked about the Line between Prose and Poetry" is frequently taught as an example of an Ars Poetica as it describes the nearly imperceptible change between rain and snow while still maintaining the formal poetic elements of rhyme and meter. A critical review by Mary Kinzie said of it: "the poem imperceptibly thickens itself out of the stream of prose."