Reviews were positive :
- Elizabeth Day in The Observer concludes that "The Francesco passages are littered with poetic fragments that pull the chronology forward and back and so out-of-shape that sometimes, it is difficult to know what is happening...Personally, I preferred George's narrative and could have happily read an entire novel which consisted of a more conventional plotting of her story. I admired the Francesco passages rather than feeling engrossed by them and occasionally it felt as if Smith's ideas were so clever they were in danger of getting in the way of the story. But there is no doubt that Smith is dazzling in her daring. The sheer inventive power of her new novel pulls you through, gasping, to the final page."[7]
- Laura Miller, in The Guardian comments on duality of the novel: "While I do not doubt the two halves of How to Be Both may be read in either order with satisfying results, once read, it's impossible to know what it would be like to first encounter it in the alternate order... How to Be Both is unforgettable. I can never know what it would be like to meet George before knowing Del Cossa, so that version of the novel is forever lost to me. It's a bit sad. But it was worth it."[8]
- Arifa Akbar in The Independent also comments on the dual narrative, writing that "Smith has written a radical novel, one that becomes two novels, with discrete meanings, through its (re)ordering... How to be Both shows us that the arrangement of a story, even when it's the same story, can change our understanding of it and define our emotional attachments. We may have known this, but to see it enacted with such imagination is dazzling indeed. Those writers making doomy predictions about the death of the novel should read Smith's re-imagined novel/s, and take note of the life it contains."[9]
- Patrick Flanery of The Telegraph finds that "The pain of mourning and loss is seared into the lives of Smith’s two motherless heroines, but despite the novel’s refusal of consolation and the profound seriousness of the questions it explores, How to be Both brims with palpable joy, not only at language, literature, and art’s transformative power, but at the messy business of being human, of wanting to be more than one kind of person at once. The possibilities unleashed by the desire to be neither one thing nor the other means that one may ever and always strive to be both. With great subtlety and inventiveness, Smith continues to expand the boundaries of the novel".[10]
- Ron Charles of The Washington Post writes that "This gender-blending, genre-blurring story, bounces across centuries, tossing off profound reflections on art and grief, without getting tangled in its own postmodern wires. It’s the sort of death-defying storytelling acrobatics that don’t seem entirely possible — How did she get here from there? — but you’ve got to be willing to hang on...This sounds like a novel freighted with postmodern gimmicks, but Smith knows how to be both fantastically complex and incredibly touching."[11]
