Stand-up comedian Paul F. Tompkins' 2009 comedy album Freak Wharf contains a track titled "Go Ask Alice" in which he derides the book as "the phoniest of balonies" and jokingly suggests it was authored by the writing staff of the police drama series Dragnet. The album title comes from a passage in the book in which the diarist refers to a mental hospital as a "freak wharf".[75]
American band Ice Nine Kills drew inspiration from the book for their song "Alice" on the 2015 album Every Trick in the Book.
Musical artist Melanie Martinez based her unreleased track, "Birthing Addicts", on the book in 2011. The song was originally written for an extra credit assignment at Melanie's school. It was meant to be on her unreleased EP, Take Me to the Moon, but was scrapped upon completion.
