The monster's grotesqueness
Frankenstein's aim was to create a beautiful creature; yet the reality of his creation was out-of-joint with this goal, and he ultimately created something grotesque. He describes this when he recounts the creation event to Walton: "How can I describe my emotions at this catastrophe, or how delineate the wretch whom with such infinite pains and care I had endeavoured to form? His limbs were in proportion, and I had selected his features as beautiful. Beautiful!--Great God! His yellow skin scarcely covered the work of muscles and arteries beneath; his hair was of a lustrous black, and flowing; his teeth of a pearly whiteness; but these luxuriances only formed a more horrid contrast with his watery eyes, that seemed almost of the same colour as the dun white sockets in which they were set, his shrivelled complexion and straight black lips" (Volume I, Chapter 5).
The monster's elocution
Largely due to the monster learning to read via Paradise Lost, he speaks in eloquent English, showing a mastery of language that one would not expect given his monstrous appearance and character.
Frankenstein's responsibility for William's death
Frankenstein sought to use science to create life; yet it was his very creation that led to the death of one of his own family members.
Progress as a destructive force
One would expect scientific progress to be socially productive; however, Frankenstein's 'achievement' of creating life leads only to death and suffering, both for his creation and the world around him.
