Flowers for Algernon has been adapted many times for different media including stage, screen, and radio. These adaptations include:
- A 1961 episode of the television drama The United States Steel Hour, "The Two Worlds of Charlie Gordon", starring Cliff Robertson.[42][43]
- A 1968 film, Charly, also starring Cliff Robertson, for which he won the Academy Award for Best Actor.[42][44]
- A 1975 stage play, Entaha El-Dars Ya Ghabi (The Lesson Is Over, Stupid) by Egyptian actor Mohamed Sobhi.
- A 1969 stage play, Flowers for Algernon by David Rogers.[42][45]
- A 1978 stage musical, Charlie and Algernon by David Rogers and Charles Strouse.[42][46][47]
- A 1979 rock opera, A Curious Feeling by Tony Banks.[48]
- A 1991 radio play, Flowers for Algernon, for BBC Radio 4 starring Tom Courtenay.[49]
- A 1991 episode of the television series Star Trek: The Next Generation, "The Nth Degree".[50]
- A 2000 television film, Flowers for Algernon, starring Matthew Modine.
- A 2001 episode of the television series The Invisible Man, "Flowers for Hobbes".
- A 2001 Spider-Man comic story, "Flowers for Rhino", by Peter Milligan and Duncan Fregredo.
- A 2002 Japanese drama, Algernon ni Hanataba o for Fuji Television, starring Yūsuke Santamaria.
- A 2005 episode of the television series SpongeBob SquarePants, "Patrick SmartPants".
- A 2006 French television film, Des fleurs pour Algernon.
- A 2013 episode of the television series It's Always Sunny in Philadelphia, "Flowers for Charlie".[51]
- A 2013 episode of the television series The League, "Flowers for Taco".
- A 2015 Japanese drama, Algernon ni Hanataba o for Tokyo Broadcasting System, starring Yamashita Tomohisa and Chiaki Kuriyama.
- A 2018 video game, NieR: Automata, titles its "A" ending Flowers for Machines.
- A 2020 episode of the television series Curb Your Enthusiasm, "Beep Panic".
Further stage and radio adaptations have been produced in France (1982), Ireland (1983), Australia (1984), Poland (1985), Japan (1987, 1990), and Czechoslovakia (1988).[42]
