- Jack Nicholson as Jack Napier / The Joker
- Hugo E. Blick as young Jack Napier
- Michael Keaton as Bruce Wayne / Batman
- Charles Roskilly as young Bruce Wayne
- Kim Basinger as Vicki Vale
- Robert Wuhl as Alexander Knox
- Pat Hingle as Commissioner Gordon
- Billy Dee Williams as Harvey Dent
- Michael Gough as Alfred Pennyworth
- Jack Palance as Carl Grissom
- Jerry Hall as Alicia Hunt
- Tracey Walter as Bob the Goon
- Lee Wallace as Mayor Borg
- William Hootkins as Lt. Max Eckhardt
- Liza Ross as tourist mom
- Garrick Hagon as tourist dad
- Adrian Meyers as tourist son
- David Baxt as Thomas Wayne
- Sharon Holm as Martha Wayne
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