- Primary characters
- William of Baskerville – main protagonist, a Franciscan friar
- Adso of Melk – narrator, Benedictine novice accompanying William
- At the monastery
- Abo of Fossanova – the abbot of the Benedictine monastery
- Severinus of Sankt Wendel – herbalist who helps William
- Malachi of Hildesheim – librarian
- Berengar of Arundel – assistant librarian
- Adelmo of Otranto – illuminator, novice
- Venantius of Salvemec – translator of manuscripts
- Benno of Uppsala – student of rhetoric
- Alinardo of Grottaferrata – eldest monk
- Jorge of Burgos – elderly blind monk
- Remigio of Varagine – cellarer
- Salvatore of Montferrat – monk, associate of Remigio
- Nicholas of Morimondo – glazier
- Aymaro of Alessandria – gossipy, sneering monk
- Pacificus of Tivoli
- Peter of Sant’Albano
- Waldo of Hereford
- Magnus of Iona
- Patrick of Clonmacnois
- Rabano of Toledo
- Outsiders
- Ubertino of Casale – Franciscan friar in exile, friend of William
- Michael of Cesena – Minister General of the Franciscans
- Bernard Gui – Inquisitor
- Bertrand del Poggetto – Cardinal and leader of the Papal legation
- Jerome of Kaffa (Jerome of Catalonia aka Hieronymus Catalani) – Bishop of Kaffa
- Peasant girl from the village below the monastery
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