The Hot Zone

The Hot Zone Glossary

abscess

an area of inflamed or swollen tissue in the body that is filled with pus

affinity

a natural liking or attraction to something

agonal

relating to agony, particularly near death

AIDS

A disease of the immune system caused by a virus. Also known as the acquired immunodeficiency virus.

alleviate

to lessen the pain of something

Andromeda strain

a hypothetical infectious pathogen with the ability to mutate unpredictably and resist destruction

antechamber

a small room leading into a larger one

anthrax

an infectious disease caused by a spore-forming bacterium

aperitif

an alcoholic beverage typically taken as an appetizer

automaton

a machine that can move independently; also a person who acts in a mechanical way

avert

to turn away

bemused

confused or preoccupied

biocontainment

the containment of materials that are potentially hazardous to life

biological agent

any virus, toxin, or bacterium that could potentially be used in biological warfare

Biosafety level

the level of containment precautions necessary to isolate biological agents in an enclosed facility.

Biosafety level 1

This level is used for biological agents that do not typically cause disease in adult humans and present minimal danger to laboratory personnel

Biosafety level 2

the level of containment precautions necessary to isolate agents of moderate danger to humans

Biosafety level 3

the level of containment precautions necessary to isolate agents that can cause serious and fatal disease in humans for which treatments exist. Examples include West Nile virus, rabies, and yellow fever.

Biosafety level 4

the level of containment precautions necessary to isolate agents that can cause severe and fatal disease in humans for which treatments do not exist. Examples include Ebola virus, Marburg virus, and smallpox.

bloat

to expand or swell

blood serum

liquid that separates from blood after it clots

botulism

a serious disease caused by eating spoiled food

cacophony

loud and harsh sounds

cadaver

a dead body

callus

a thick, hardened part of the skin

carnage

extensive slaughter or death

claustrophobia

fear of small or enclosed spaces

coagulate

to change from a liquid to a thickened mass

conduit

a pipe or tube, typically for conveying fluid

contemplate

to consider thoughtfully

contention

dispute or disagreement

corrugated

wrinkled or folded

crash and bleed

military slang meaning to hemorrhage from multiple orifices before dying suddenly

cringing

to shrink back or cower

cryptic

mysterious or secret

dappled

covered in spots of different shapes and colors

decontamination

the process of cleaning an object to remove biological hazards and other harmful substances

delirious

suffering from a disorder of the mental faculties (often caused by fever)

dementia

loss of intellectual capacity due to brain damage

depersonalize

to deprive of individuality and personality

despondent

hopeless

deteriorate

to worsen over time

dialysis

the medical process of removing blood from a person, cleaning it, and returning it to the person

diamond knife

a sharp knife with an edge made from diamond. Frequently used for scientific and medical procedures.

diatribe

a bitter verbal attack

disheveled

untidy

dregs

the last remaining part

ebola

a lethal filovirus from the tropics with three known sub-types: Ebola Zaire, Ebola Sudan, and Ebola Reston. Closely related to the Marburg virus.

enigma

difficult to understand or explain

envirochem

liquid disinfectant used in chemical showers.

epicenter

focal point

epistaxis

nose bleed

euthanize

to kill, often in order to end suffering

expatriate

a resident in a foreign country; also, an exiled person

extreme amplification

multiplication of a virus throughout the host

febrile

feverish

ferocity

fierceness

filovirus

In Latin, "thread virus." The filovirus family consists of four simlar viruses: Marburg, Ebola Zaire, Ebola Sudan, and Ebola Reston. Each strain consists of seven proteins, four of which are unknown.

gangrene

the decay of tissue caused by a lack of blood supply

grackle

a type of blackbird

guano

excrement or dung from birds and bats, frequently used as fertilizer

gurney

a wheeled stretcher used to transport patients

hemophilia

a genetic disorder that affects blood clotting

hemorrhage

severe bleeding that is difficult to control

hemostat

a surgical clamp used to constrict blood vessels

HIV

human immunodeficiency virus. A retrovirus that causes AIDS by infecting the immune system.

host

a plant or animal that harbors a parasite, such as a virus

hostile

angry and aggressive

hot agent

a deadly virus for which there is no vaccine and no cure

hot zone; hot area

an area containing lethal and/or infectious organisms

ICU

intensive care unit

imperceptible

difficult to perceive

implacable

impossible to appease or calm

incinerate

to burn to ashes

incubation

the development of an infectious disease or virus from the time of infection through the appearance of symptoms

index case

the first known case in a viral outbreak

inscrutable

difficult to understand

invasive

displaying a tendency to spread into healthy tissue

jaundice

a medical condition in which a person's skin and eyes turn yellow

laryngoscope

a medical instrument used to examine the larynx

lesion

an infected patch of skin

lethargy

a state of inactivity and apathy

liquefaction

the process of turning into a liquid

Marburg virus

A virus that first appeared at the Behring Works vaccine factory in Marburg, Germany in 1967 and demonstrated a 1 in 4 kill rate. Belongs to a family of viruses known as the filoviruses.

mattock

a digging tool with a flat blade

Mayinga strain

A particularly deadly strain of Ebola virus, named for a nurse who died from it in 1976.

monosyllabic

using short, one-syllable words

necropsy

the examination of a body after death

nimble

quick and light in movement

oblong

an object with an elongated shape, such as a rectangle or an ellipse

opalescent

displaying a milky shimmer similar to an opal

parasite

an organism that lives on or inside another species

paroxysm

an outburst of emotion; also, a sudden attack by a disease

pastoral

relating to country-life; rural

pathologist

A scientist who studies the nature of disease and its causes

petechiae

a purplish spot on the skin caused by a small hemorrhage

prehensile

adapted for grabbing or holding

promontory

a ridge of land that juts out into a body of water

putrid

rotten

quarantine

enforced isolation to prevent the spread of a contagious disease

racal suit

a space suit with a battery-powered air supply used for biohazard fieldwork

ravage

devastate

recurrent

happening again or repeatedly

regurgitate

to throw up or vomit

replicate

to make exact copies of

rongeur

Forceps used to cut through bone and heavy tissue. In French, "gnawer."

savanna

a tropical grassland

scrutinize

to examine closely

sentinel animal

an animal used to detect risk to humans from an environmental factor, such as a virus.

SHF

Simian hemorrhagic fever. A virus found in monkeys that is harmless to humans.

silo

a tall structure used for storing feed

skeptical

given to doubt or questioning

slough

to shed or cast off

spleen

an organ near the stomach that produces white blood cells

sputum

a combination of saliva and mucus expelled from the lungs

sullen

sulky and bad-tempered

tarpaulin

a large piece of waterproof material used to cover things

unequivocal

strong and clear, without doubt

USAMRIID

The United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, in Frederick, Maryland. Also referred to as "the Institute."

vector

a carrier or transporter of a virus

vomito negro

black vomit associated with the ebola virus and yellow fever