- Humphrey Bogart as Charlie Allnut
- Katharine Hepburn as Rose Sayer
- Robert Morley as Reverend Samuel Sayer, "The Brother"
- Peter Bull as the Captain of the Königin Luise
- Theodore Bikel as the First Officer of the Königin Luise
- Walter Gotell as the Second Officer of the Königin Luise
- Peter Swanwick as the First Officer of Fort Shona
- Richard Marner as the Second Officer of Fort Shona
- Gerald Onn as Petty Officer of the Königin Luise (uncredited)[10]
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