Answer
Oligonucleotide probes, short artificial DNA sequences, are hybridized with the denatured PCR products. The probe is marked with a stain or isotope so that hybridization can be easily detected, allowing for efficient diagnosis of a genetic disease while offering an individual vital information about his or her genome.
Work Step by Step
Oligonucleotide probes, short artificial DNA sequences, are hybridized with the denatured PCR products. The probe is marked with a stain or isotope so that hybridization can be easily detected, allowing for efficient diagnosis of a genetic disease while offering an individual vital information about his or her genome.