Life: The Science of Biology 11th Edition

Published by W. H. Freeman
ISBN 10: 1-31901-016-4
ISBN 13: 978-1-31901-016-4

Chapter 15 - Gene Mutation and Molecular Medicine - 15.4 - Genetic Screening Is Used to Detect Diseases - 15.4 Recap - Learning Outcomes - Page 331: 2

Answer

Oligonucleotide probes, short artificial DNA sequences, are hybridized with the denatured PCR products. The probe is marked with a stain or isotope so that hybridization can be easily detected, allowing for efficient diagnosis of a genetic disease while offering an individual vital information about his or her genome.

Work Step by Step

Oligonucleotide probes, short artificial DNA sequences, are hybridized with the denatured PCR products. The probe is marked with a stain or isotope so that hybridization can be easily detected, allowing for efficient diagnosis of a genetic disease while offering an individual vital information about his or her genome.
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