Chapter 11 - The Cell Cycle and Cell Division - 11.2 - The Eukaryotic Cell Division Cycle IS Regulated - 11.2 Recap - Learning Outcomes - Page 219: 2

Cdk is an enzyme that catalyzes the transfer of a phosphate group from ATP to a protein in a process called phosphorylation. Cdk’s need to be activated by binding to a cyclin protein. An example of allosteric regulation, this binding activates the Cdk by changing the shape of its active site. As a result, the retinoblastoma protein is inhibited in association with cell cycle checkpoints that allows the cell to progress.

Cdk is an enzyme that catalyzes the transfer of a phosphate group from ATP to a protein in a process called phosphorylation. Cdk’s need to be activated by binding to a cyclin protein. An example of allosteric regulation, this binding activates the Cdk by changing the shape of its active site. As a result, the retinoblastoma protein is inhibited in association with cell cycle checkpoints that allows the cell to progress.