Human Anatomy & Physiology (9th Edition)

Published by Pearson
ISBN 10: 0321743261
ISBN 13: 978-0-32174-326-8

Chapter 12 - The Central Nervous System - Review Questions - Critical Thinking and Clinical Application Questions - Page 481: 5b


The basic deficit is loss of dopamine secreting neurons of the substantia nigra.

Work Step by Step

Loss of dopamine and increase in GABA secretion in Parkinson,s disease lead to hyperactivity of the basal nuclei of the mid brain with associated involuntary muscle contractions (tremors).
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