U.S. astronauts Frank Borman and Jim Lovell read Roughing It aloud to pass the time aboard NASA's Gemini VII, a 14-day-long Earth orbital mission in December 1965.[5]
In Lords of St. Thomas, a 2018 historical novel set in St. Thomas, Nevada, the main character "Little" Henry Lord is reading Roughing It when he learns that his father has fallen from the Hoover Dam.