Walter Leyden Brown[20] directed a theatrical adaptation of the book at La MaMa Experimental Theatre Club in Manhattan's East Village in 1974.[21]
The book was the source for the 1999 French film Pola X and its extended cut for television, Pierre ou, Les ambiguïtés, both directed by Leos Carax.
The Denver Center Theatre Company developed and produced the world premiere of Pierre in 2002, a stage play written by Jeffrey Hatcher, and directed by Bruce K. Sevy. The cast included Christopher Kelly as Pierre Glendinning and Morgan Hallett as Isabel Banford.
American composer Richard Beaudoin wrote an opera based on the book; Act I was staged in August 2007 at London's Arcola Theatre.
