The novel was adapted into a 1963 play, starring Kirk Douglas (who purchased the rights to produce it for the stage and motion pictures) as McMurphy and Gene Wilder as Billy Bibbit. A film adaptation, starring Jack Nicholson and co-produced by Michael Douglas, was released in 1975. The film won five Academy Awards.
The characters of Nurse Ratched and Chief Bromden appear as recurring characters in ABC's Once Upon a Time, where they are portrayed by Ingrid Torrance and Peter Marcin.
Netflix and Ryan Murphy produced a prequel series titled Ratched which follows Sarah Paulson as a younger version of Nurse Ratched.[14] The first of the two-season order was released on September 18, 2020.