- Dick Powell as Philip Marlowe
- Claire Trevor as Helen Grayle/Velma Valento
- Anne Shirley as Ann Grayle
- Otto Kruger as Jules Amthor
- Mike Mazurki as Moose Malloy
- Miles Mander as Mr. Grayle
- Douglas Walton as Lindsay Marriott
- Don Douglas as Police Lt. Randall
- Ralf Harolde as Dr. Sonderborg
- Esther Howard as Mrs. Jessie Florian
- John Indrisano as chauffeur (Amthor's henchman)
- Dewey Robinson as New Boss at 'Florian's' (uncredited)
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