- Metropolis (surname)
- Metropolis (Grosz), a 1916-1917 painting by George Grosz
- Metropolis (Dix), a 1928 painting by Otto Dix
- Metropolis (religious jurisdiction) or episcopal see, the seat of a (metropolitan) bishop
- Metropolis Asia, an annual arts festival held in Guwahati, India
- Metropolis Coffee Company, a specialty coffee company in Chicago, Illinois
- Metropolis in France, a form of intercommunality in France
- Metropolis Group, holding company for Metropolis Studios, a recording studio in London
- Metropolis International, a predominantly UK-based media and technology group
- Metropolis Lab, an Indian multinational chain of diagnostic companies
- Metropolis Ltd, an American game company
- Metropolis Performing Arts Centre, a professional theatre company in Arlington Heights, Illinois
- Metropolis Project, a research network studying human migration
- Metropolis RFC, an American rugby team based in Minneapolis
- Alstom Metropolis, a type of metro train
- City New South Wales rugby league team or Metropolis
- Palantir Metropolis, a business software product
- Metropolis–Hastings algorithm, a statistical method
- Metropolis Zone, a level in Sonic the Hedgehog 2
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