The soundtrack to Good Night, and Good Luck was released on September 27, 2005. The film's score was composed by Jim Papoulis.
| No. | Title | Artist | Length |
|---|---|---|---|
| 1. | "Straighten Up and Fly Right" | Dianne Reeves | 2:44 |
| 2. | "I've Got My Eyes on You" | Dianne Reeves | 2:06 |
| 3. | "Gotta Be This or That" | Dianne Reeves | 3:16 |
| 4. | "Too Close for Comfort" | Dianne Reeves | 3:50 |
| 5. | "How High the Moon" | Dianne Reeves | 2:22 |
| 6. | "Who's Minding the Store?" | Dianne Reeves | 4:31 |
| 7. | "You're Driving Me Crazy" | Dianne Reeves | 1:57 |
| 8. | "Pretend" | Dianne Reeves | 4:01 |
| 9. | "Solitude" | Dianne Reeves | 5:28 |
| 10. | "TV Is the Thing This Year" | Dianne Reeves | 1:43 |
| 11. | "Pick Yourself Up" | Dianne Reeves | 2:38 |
| 12. | "When I Fall in Love" | Dianne Reeves | 3:52 |
| 13. | "Into Each Life Some Rain Must Fall" | Dianne Reeves | 4:08 |
| 14. | "There'll Be Another Spring" | Dianne Reeves | 4:43 |
| 15. | "One for My Baby" | Dianne Reeves | 3:50 |
| Total length: | 51:09[8] |
