Playhouse 90 broadcast "A Sound of Different Drummers" on CBS in 1957, written by Robert Alan Aurthur. The play combined plot ideas from Fahrenheit 451 and Nineteen Eighty-Four. Bradbury sued and eventually won on appeal.
In the kids sitcom iCarly, it is stated in the episode “iFind Spencer Friends” that Spencer Shay is kicked out of his book club for burning a whole box of Fahrenheit 451.
A film adaptation written and directed by François Truffaut and starring Oskar Werner and Julie Christie was released in 1966.
A new film adaptation directed by Ramin Bahrani and starring Michael B. Jordan, Michael Shannon, Sofia Boutella, and Lilly Singh was released in 2018 for HBO.
In the late 1970s Bradbury adapted his book into a play. At least part of it was performed at the Colony Theatre in Los Angeles in 1979, but it was not in print until 1986 and the official world premiere was only in November 1988 by the Fort Wayne, Indiana Civic Theatre. The stage adaptation diverges considerably from the book and seems influenced by Truffaut's movie. For example, fire chief Beatty's character is fleshed out and is the wordiest role in the play. As in the movie, Clarisse does not simply disappear but in the finale meets up with Montag as a book character (she as Robert Louis Stevenson, he as Edgar Allan Poe).
The UK premiere of Bradbury's stage adaptation was not until 2003 in Nottingham, while it took until 2006 before the Godlight Theatre Company produced and performed its New York City premiere at 59E59 Theaters. After the completion of the New York run, the production then transferred to the Edinburgh Festival where it was a 2006 Edinburgh Festival Pick of the Fringe.
The Off-Broadway theatre The American Place Theatre presented a one man show adaptation of Fahrenheit 451 as a part of their 2008–2009 Literature to Life season.
Fahrenheit 451 inspired the Birmingham Repertory Theatre production Time Has Fallen Asleep in the Afternoon Sunshine, which was performed at the Birmingham Central Library in April 2012.
BBC Radio produced a one-off dramatization of the novel in 1982 starring Michael Pennington. It was broadcast again on February 12, 2012, and April 7 and 8, 2013, on BBC Radio 4 Extra.
In 1984, the novel was adapted into a computer text adventure game of the same name by the software company Trillium.
In June 2009, a graphic novel edition of the book was published. Entitled Ray Bradbury's Fahrenheit 451: The Authorized Adaptation, the paperback graphic adaptation was illustrated by Tim Hamilton. The introduction in the novel is written by Bradbury.