- 1848 - a play adaptation by John Brougham that premiered at Burton's Theatre in July 1848 with William Evans Burton as Captain Cuttle
- 1969 miniseries – starring John Carson as Paul Dombey and Derek Seaton as Walter Gay
- 1974 – Dombi i syn a Soviet teleplay starring Valentin Gaft as Paul Dombey and Konstantin Raikin as Walter Gay
- 1983 miniseries – starring Julian Glover as Paul Dombey and Max Gold as Walter Gay
- 2007 - Dombais et fils a French television mini-series starring Christophe Malavoy as Charles Dombais (=Paul Dombey)
- 1917 – Dombey and Son a British Silent film starring Norman McKinnel as Paul Dombey and Hayford Hobbs as Walter Gay
- 1931 – Rich Man's Folly a loose adaptation of the novel which is modernised and set in the United States
- 2007, a twenty-part BBC Radio 4 adaptation written by Mike Walker, with Alex Jennings as the voice of Charles Dickens, Robert Glenister as Dombey, Abigail Hollick as Florence, Helen Schlesinger as Edith, Trevor Peacock as Captain Cuttle, Adrian Luker as Carker, Geraldine James as Mrs. Brown and Sam Pamphilon as Toots.