Kamble formed Dalit Panther of India as a social organisation alongside Namdeo Dhasal and Raja Dhale in 1976. Later Kamble became the National General Secretary of Janata Dal and worked with former Prime Minister V.P. Singh. He demanded the renaming of Marathwada University to "Dr. Babasaheb Ambedkar University". Kamble, a writer, poet and editor, authored many books such as Cultural Struggle in Ramayana, Conversion of Dr. Babasaheb Ambedkar, Cheevar, Vaad-Samvad, Yug-Pravartak Ambedkar, Chalvaliche Diwas, and Tarkateerth Ek Vadato-Vyaghyat. He was awarded with many accolades such as "The Prabuddha Ratna Puraskar", Life Time Achievement International Award. Some of his works have been translated into English, German, French, Gujarati, Kannada, Telugu, Malayalam, Urdu (Dalit Awaaz) and Hindi (Suraj ke Vansh-dhar).
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