Hi, I'm wondering what is the function of a liposome? who can tell me detailed information? Any help would be appreciated. Thanks in advance!
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1.Targeting and lymphatic orientation: passive targeting of the liver and spleen reticuloendothelial system. It is used for the prevention and treatment of diseases of mononuclear-macrophage system such as hepatic parasitic diseases and leishmaniasis. For example, the liver leishmania prodrug citrate liposome has a liver concentration that is 200-700 times higher than that of the common preparation.
2.sustained release: slow release, delay renal excretion and metabolism, thereby prolonging the duration of action.
3. reduce drug toxicity: such as amphotericin B liposome can reduce cardiotoxicity.
4. improve stability: such as insulin liposomes, vaccines, etc. can improve the stability of the main drug.