Hi, I'm wondering What advantages do lipoparticles have in isolating membrane proteins? who can tell me detailed information? Any help would be appreciated. Thanks in advance!
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Firstly, they are homogeneous and physically well defined, capable of maintaining the native structures of target membrane proteins in high densities; secondly, they can be used to detect membrane protein interactions and therefore have wide applications in antibody screening, phage and yeast display, immunogens production and ligand binding assays.