(Alphabetical by artist)
- The Boston Crusaders Drum and Bugle Corps' 2014 show was titled Animal Farm, based on the novel.
- Canadian-based band Boxer the Horse takes its name from a character in the novel.
- Dead prez based a song on their album Let's Get Free (2000), called "Animal in Man", on the novella, putting emphasis on how the other animals should not trust the pigs during a revolution.
- The lyrics of the song ″Arthur's Farm″ from the Half Man Half Biscuit album Back Again in the DHSS (1987) tell the story of Douglas Bader and Arthur Askey visiting Animal Farm. The song features the line "Four legs good, but no legs best" in apparent tribute to the two famous amputees.
- The song, "The Nature of the Beast", by the American metalcore band, Ice Nine Kills, was inspired by Animal Farm.
- Pink Floyd's album Animals (1977) was partially inspired by Animal Farm. It categorises people as pigs, dogs, or sheep.
- R.E.M.'s song "Disturbance at the Heron House" is based on Animal Farm.
- Radiohead's song "Optimistic" contains a lyric mentioning Animal Farm.
- The Clash used an image from the animated movie Animal Farm (1954) on their single "English Civil War".
(Alphabetical by program)
- In The Daleks' Master Plan (1966), an episode of the long-running British science fiction show Doctor Who, a character references the modified seventh commandment of Animal Farm, saying: "Though we are all equal partners with the Daleks on this great conquest, some of us are more equal than others."
- In the tenth episode of the second season of Johnny Bravo, "Aunt Katie's Farm" (1999), Johnny, while dressed in a pig costume, yells, "Four feet good! Two feet bad!".
- The Lost episode "Exposé" (2007), in season three, involves flashbacks with Nikki and Paulo involving an argument with Kate about the handgun case. During this scene, Dr. Leslie Arzt yells at Kate: "The pigs are walking," a reference to Animal Farm where Napoleon and his generals begin to adapt human characteristics and change their oath from "Four legs good, two legs bad" to "Four legs good, two legs better."
- The seventh episode (1998) of the second season of the HBO series Oz is titled "Animal Farm" in reference to the conniving and manipulation of the characters vying for control, similar to the characters of the novella.
- In the ninth episode of the fourth season of Sex and the City, "Sex and the Country" (2001), Carrie goes with her new boyfriend Aidan to his cottage, and informs her friends that it reminds her of Animal Farm, and would not be surprised to hear an outburst of "four legs good, two legs bad!"
- In the third episode of the first season of the X-Men animated series, "Enter Magneto" (1992), Beast is seen reading a copy of Animal Farm, is mocked by the prison guards for "reading a picture book", and is asked if he "sees any relatives in there" because they assume he is an illiterate animal.
A video game adaptation of Animal Farm was announced in August 2017. Fully authorised by the estate of George Orwell, Animal Farm is created by an independent team formed specifically to deliver Orwell’s vision in an interactive format.