- Marcello Mastroianni as Guido Anselmi, a film director
- Claudia Cardinale as Claudia, a film star Guido casts as his Ideal Woman
- Anouk Aimée as Luisa Anselmi, Guido's estranged wife
- Sandra Milo as Carla, Guido's mistress
- Rossella Falk as Rossella, Luisa's best friend and Guido's confidante
- Barbara Steele as Gloria Morin, Mezzabotta's new young girlfriend
- Madeleine Lebeau as Madeleine, a French actress
- Caterina Boratto as a mysterious lady in the hotel
- Eddra Gale as La Saraghina, a prostitute
- Guido Alberti as Pace, a film producer
- Mario Conocchia as a fictionalized version of himself, Guido's production assistant
- Bruno Agostini as a fictionalized version of himself, the production director
- Cesarino Miceli Picardi as a fictionalized version of himself, the production supervisor
- Jean Rougeul as Carini Daumier, a film critic
- Mario Pisu as Mario Mezzabotta, Guido's friend
- Yvonne Casadei as Jacqueline Bonbon, a former cabaret dancer
- Ian Dallas as Maurice, Maya's assistant
- Mino Doro as Alberto, Claudia's agent
- Nadia Sanders as Nadine
- Edy Vessel as a mannequin
- Eugene Walter as an American journalist
- Mary Indovino as Maya, the clairvoyant
- Giuditta Rissone as Guido's mother
- Annibale Ninchi as Guido's father
- Olimpia Cavalli as Olimpia (uncredited)
- Ferdinand Guillaume as the clown (uncredited)
- Maria Antonietta Beluzzi as a prostitute (uncredited)
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