Uncle Tom's Cabin Harriet Stowe

Eliza escapes with her son; Tom sold "down the river"

The book opens with a Kentucky farmer named Arthur Shelby facing the loss of his farm because of debts. Even though he and his wife Emily Shelby believe that they have a benevolent relationship with their slaves, Shelby decides to raise the needed funds by selling two of them—Uncle Tom, a middle-aged man with a wife and children, and Harry, the son of Emily Shelby's maid Eliza—to Mr. Haley, a coarse slave trader. Emily Shelby is averse to this idea because she had promised her maid that her child would never be sold; Emily's son, George Shelby, hates to see Tom go because he sees the man as his friend and mentor.

When Eliza overhears Mr. and Mrs. Shelby discussing plans to sell Tom and Harry, Eliza determines to run away with her son. The novel states that Eliza made this decision because she fears losing her only surviving child (she had already miscarried two children). Eliza departs that night, leaving a note of apology to her mistress. She later makes a dangerous crossing over the ice of the Ohio River to escape her pursuers.

As Tom is sold, Mr. Haley takes him to a riverboat on the Mississippi River and from there Tom is to be transported to a slave market. While on board, Tom meets Eva, an angelic little white girl. They quickly become friends. Eva falls into the river and Tom dives into the river to save her life. Being grateful to Tom, Eva's father Augustine St. Clare buys him from Haley and takes him with the family to their home in New Orleans. Tom and Eva begin to relate to one another because of the deep Christian faith they both share.

Eliza's family hunted; Tom's life with St. Clare

During Eliza's escape, she meets up with her husband George Harris, who had run away previously. They decide to attempt to reach Canada, but are tracked by Tom Loker, a slave hunter hired by Mr. Haley. Eventually Loker and his men trap Eliza and her family, causing George to shoot him in the side. Worried that Loker may die, Eliza convinces George to bring the slave hunter to a nearby Quaker settlement for medical treatment.

Back in New Orleans, St. Clare debates slavery with his Northern cousin Ophelia who, while opposing slavery, is prejudiced against black people. St. Clare, however, believes he is not biased, even though he is a slave owner. In an attempt to show Ophelia that her prejudiced views against black people are wrong, St. Clare purchases Topsy, a young black slave, and asks Ophelia to educate her.

After Tom has lived with the St. Clares for two years, Eva grows very ill. Before she dies she experiences a vision of heaven, which she shares with the people around her. As a result of her death and vision, the other characters resolve to change their lives, Ophelia promising to throw off her personal prejudices against blacks, Topsy saying she will better herself, and St. Clare pledging to free Tom.

Tom sold to Simon Legree

Before St. Clare can follow through on his pledge, he dies after being stabbed outside a tavern. His wife reneges on her late husband's vow and sells Tom at auction to a vicious plantation owner named Simon Legree. Tom is taken to rural Louisiana with other new slaves including Emmeline, whom Simon Legree has purchased to use as a sex slave.

Legree begins to hate Tom when Tom refuses Legree's order to whip his fellow slave. Legree beats Tom viciously and resolves to crush his new slave's faith in God. Despite Legree's cruelty, Tom refuses to stop reading his Bible and comforting the other slaves as best he can. While at the plantation, Tom meets Cassy, another slave whom Legree used as a sex slave. Cassy tells her story to Tom. She was previously separated from her son and daughter when they were sold. She became pregnant again but killed the child because she could not tolerate having another child separated from her.

Tom Loker, changed after being healed by the Quakers, returns to the story. He has helped George, Eliza, and Harry enter Canada from Lake Erie and become free. In Louisiana, Uncle Tom almost succumbs to hopelessness as his faith in God is tested by the hardships of the plantation. He has two visions, one of Jesus and one of Eva, which renew his resolve to remain a faithful Christian, even unto death. He encourages Cassy to escape, which she does, taking Emmeline with her. When Tom refuses to tell Legree where Cassy and Emmeline have gone, Legree orders his overseers to kill Tom. As Tom is dying, he forgives the overseers who savagely beat him. Humbled by the character of the man they have killed, both men become Christians. George Shelby, Arthur Shelby's son, arrives to buy Tom's freedom, but Tom dies shortly after they meet.

Final section

On their boat ride to freedom, Cassy and Emmeline meet George Harris' sister Madame de Thoux and accompany her to Canada. Madame de Thoux and George Harris were separated in their childhood. Cassy discovers that Eliza is her long-lost daughter who was sold as a child. Now that their family is together again, they travel to France and eventually Liberia, the African nation created for former American slaves. George Shelby returns to the Kentucky farm, where after his father's death, he frees all his slaves. George Shelby urges them to remember Tom's sacrifice every time they look at his cabin. He decides to lead a pious Christian life just as Uncle Tom did.