According to Marks what troubles the trade and what would be the greatest improvement?
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From the text:
"This yer young-un business makes lots of trouble in the trade," said Haley, dolefully.
"If we could get a breed of gals that didn't care, now, for their young uns," said Marks; "tell ye, I think 't would be 'bout the greatest mod'rn improvement I knows on,"—and Marks patronized his joke by a quiet introductory sniggle.
Uncle Tom's Cabin